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Literature summary extracted from

  • Roepstorff, C.; Vistisen, B.; Donsmark, M.; Nielsen, J.N.; Galbo, H.; Green, K.A.; Hardie, D.G.; Wojtaszewski, J.F.; Richter, E.A.; Kiens, B.
    Regulation of hormone-sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise (2004), J. Physiol., 560, 551-562.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.79 additional information Homo sapiens the enzyme catalyses the hydrolysis of myocellular triacylglycerol, which is a potential energy source diuring exercise ?
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?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.79 Homo sapiens
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-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.1.79 phosphoprotein 5'AMP-activated protein kinase phosphorylates hormone-sensitive lipase on Ser565 in human skeletal muscle during exercise with reduced muscle glycogen. Ser565 phosphorylation by 5'AMP-activated protein kinase during exercise has no effect on activity of hormone-sensitive lipase Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.79 skeletal muscle
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Homo sapiens
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.79 additional information the enzyme catalyses the hydrolysis of myocellular triacylglycerol, which is a potential energy source diuring exercise Homo sapiens ?
-
?